A formal synthesis of castanospermine using an olefin metathesis cyclisation reaction as a key step

DOI: 10.1016/0040-4039(95)02237-6

Source and publish data:

Tetrahedron Letters p. 547 - 550 (1996)

Update date:2022-08-04

Topics:

Authors:

Overkleeft, Herman S.

Pandit, Upendra K.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(95)02237-6

The formal synthesis of castanospermine (1) starting from tetrabenzylgluconolactam (3) is described. Olefin metathesis cyclisation reaction of dialkene 9, derived from 3, leads to indolizidinone 10, which can be used as a key intermediate for the synthesis of castanospermine (1) and its analogues.

Full text of DOI:10.1016/0040-4039(95)02237-6

Products guided by the article

Product name:(3R,4S,5R,6R)-1-Allyl-3,4,5-tris-benzyloxy-6-benzyloxymethyl-piperidin-2-one

Cas No:174504-14-4

R&D Labs maybe for 174504-14-4

Shanghai Dynamic Industrial Co.,Ltd.

website:http://www.shdynamic.com

Contact:86-021 3392 6680

Address:Room 805 Information Tower, No.1403 Minsheng Road, Pudong New Area, Shanghai 200135, P. R. China
Suzhou CarbonWell Pharma-Tech Co., Ltd

Contact:Tel: + 86 (0)512-8898-1216; + 86-18606258602

Address:2358 Changan Road, Wujiang Scientific Innovation Park, Wujiang, Jiangsu Province, P. R. China 215200
Jiaxing Anrui Material Technology Co., Ltd.

Contact:86-573-82651652 13305832579

Address:Room 407, Technology Building, 1369 Chennan Road, Jiaxing City, Zhejiang, China
JIEJIE GROUP CO.,LTD.

Contact:+86 021-51698675

Address:1701, Jielong Plaza, No.618 Pingliang Rd, ShangHai,China
Esuccess Material Limited

Contact:852-29282288

Address:HONGKONG

Relevant to this article

Isolation, structure, and synthesis of hymenoxin, a new flavone from Hymenoxys scaposa (Compositae).

Doi:10.1021/jo01285a092
(1967)
Synthesis and antimicrobial activity of some new 4-triazolylmethoxy-2H- chromen-2-one derivatives

Doi:10.1007/s00044-011-9881-0
(2012)
Efficient microwave-assisted synthesis of ionic esterified amino acids

Doi:10.3390/molecules16108733
(2011)
Hydroxylated terphenylphosphine ligands for palladium-catalyzed ortho-selective cross-coupling of dibromophenols, dibromoanilines, and their congeners with Grignard reagents

Doi:10.1016/j.tet.2011.09.013
(2011)
From virtual to physical: Integration of chemical logic gates

Doi:10.1002/anie.201104228
(2011)
Discovery of a novel class of phosphodiesterase 10A inhibitors and identification of clinical candidate 2-[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3- yl)-phenoxymethyl]-quinoline (PF-2545920) for the treatment of schizophrenia

Doi:10.1021/jm900521k
(2009)

Article Doi