A formal synthesis of castanospermine using an olefin metathesis cyclisation reaction as a key step

DOI: 10.1016/0040-4039(95)02237-6

Source and publish data:

Tetrahedron Letters p. 547 - 550 (1996)

Update date:2022-08-04

Topics:

Authors:

Overkleeft, Herman S.

Pandit, Upendra K.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(95)02237-6

The formal synthesis of castanospermine (1) starting from tetrabenzylgluconolactam (3) is described. Olefin metathesis cyclisation reaction of dialkene 9, derived from 3, leads to indolizidinone 10, which can be used as a key intermediate for the synthesis of castanospermine (1) and its analogues.

Full text of DOI:10.1016/0040-4039(95)02237-6

Products guided by the article

Product name:(3R,4S,5R,6R)-1-Allyl-3,4,5-tris-benzyloxy-6-benzyloxymethyl-piperidin-2-one

Cas No:174504-14-4

R&D Labs maybe for 174504-14-4

Linyi Shengxin Pharmaceutical R&D Co., Ltd

Contact:+86-18653953873

Address:West First of Yufeng Road, Yishui County
ANHUI WEICHI CHEMICAL CO.,LTD

website:http://www.weichichem.com

Contact:+8613912949432

Address:Fine Chemical Industrial Base,Wujiang town,He County,Anhui China.
Shandong LuZhou Amino Acid Co., Ltd

Contact:86-539-2218025

Address:yishui economic and technical development zone zhenxing south road
TIANJIN NORTH JINHENG CHEMICAL PLANT.

Contact:0086-22-59952083

Address:DongShigu Country In JiXian TianJin China
Jinan Yijialian Economic and Trade Development Co., Ltd.

Contact:+86 0531-66729596

Address:jinan

Relevant to this article

Isolation, structure, and synthesis of hymenoxin, a new flavone from Hymenoxys scaposa (Compositae).

Doi:10.1021/jo01285a092
(1967)
Synthesis and antimicrobial activity of some new 4-triazolylmethoxy-2H- chromen-2-one derivatives

Doi:10.1007/s00044-011-9881-0
(2012)
Efficient microwave-assisted synthesis of ionic esterified amino acids

Doi:10.3390/molecules16108733
(2011)
Hydroxylated terphenylphosphine ligands for palladium-catalyzed ortho-selective cross-coupling of dibromophenols, dibromoanilines, and their congeners with Grignard reagents

Doi:10.1016/j.tet.2011.09.013
(2011)
From virtual to physical: Integration of chemical logic gates

Doi:10.1002/anie.201104228
(2011)
Discovery of a novel class of phosphodiesterase 10A inhibitors and identification of clinical candidate 2-[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3- yl)-phenoxymethyl]-quinoline (PF-2545920) for the treatment of schizophrenia

Doi:10.1021/jm900521k
(2009)

Article Doi