
Tetrahedron Letters p. 547 - 550 (1996)
Update date:2022-08-04
Topics:
Overkleeft, Herman S.
Pandit, Upendra K.
The formal synthesis of castanospermine (1) starting from tetrabenzylgluconolactam (3) is described. Olefin metathesis cyclisation reaction of dialkene 9, derived from 3, leads to indolizidinone 10, which can be used as a key intermediate for the synthesis of castanospermine (1) and its analogues.
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