A formal synthesis of castanospermine using an olefin metathesis cyclisation reaction as a key step

DOI: 10.1016/0040-4039(95)02237-6

Source and publish data:

Tetrahedron Letters p. 547 - 550 (1996)

Update date:2022-08-04

Topics:

Authors:

Overkleeft, Herman S.

Pandit, Upendra K.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(95)02237-6

The formal synthesis of castanospermine (1) starting from tetrabenzylgluconolactam (3) is described. Olefin metathesis cyclisation reaction of dialkene 9, derived from 3, leads to indolizidinone 10, which can be used as a key intermediate for the synthesis of castanospermine (1) and its analogues.

Full text of DOI:10.1016/0040-4039(95)02237-6

Products guided by the article

Product name:(3R,4S,5R,6R)-1-Allyl-3,4,5-tris-benzyloxy-6-benzyloxymethyl-piperidin-2-one

Cas No:174504-14-4

R&D Labs maybe for 174504-14-4

Shanghai Dano Pharmaceutical Co.,Ld.(expird)

Contact:+86-592-6266840

Address:Building 1 Room 512, 720 Cailun Rd, Zhangjiang High-Tech Park, Shanghai 201203, China
Anhui Redstar Pharmaceutical Corp., Ltd

Contact:+86-563-5120837

Address:Jingxian Industrial Development Zone, Anhui , China
Nanjing Chemical Material Corp.(NCMC)

website:http://www.njchemm.com

Contact:0086-25-83172879

Address:B12 Technology and Innovation Building, Nanjing Tech University, No.5 New Model Road
Tangshan Wisdom Trading Co.,Ltd

Contact:86 315 2222979

Address:No.41 BeiXinXi Road, Yangguang building 1-1102 , Tangshan, Hebei, China
SHIJIAZHUANG CHENSHI IMPORT AND EXPORT CO.,LTD

Contact:+86-311-89871056

Address:RM2017 BUILDING CTIANSHAN GALAXY PLAZA,NO168 CHANGJIANG ROAD,GAOXIN DISTRICT,SHIJIAZHUANG CITY, HEBEI,CHINA

Relevant to this article

Isolation, structure, and synthesis of hymenoxin, a new flavone from Hymenoxys scaposa (Compositae).

Doi:10.1021/jo01285a092
(1967)
Synthesis and antimicrobial activity of some new 4-triazolylmethoxy-2H- chromen-2-one derivatives

Doi:10.1007/s00044-011-9881-0
(2012)
Efficient microwave-assisted synthesis of ionic esterified amino acids

Doi:10.3390/molecules16108733
(2011)
Hydroxylated terphenylphosphine ligands for palladium-catalyzed ortho-selective cross-coupling of dibromophenols, dibromoanilines, and their congeners with Grignard reagents

Doi:10.1016/j.tet.2011.09.013
(2011)
From virtual to physical: Integration of chemical logic gates

Doi:10.1002/anie.201104228
(2011)
Discovery of a novel class of phosphodiesterase 10A inhibitors and identification of clinical candidate 2-[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3- yl)-phenoxymethyl]-quinoline (PF-2545920) for the treatment of schizophrenia

Doi:10.1021/jm900521k
(2009)

Article Doi