Journal of the Chemical Society. Perkin transactions I p. 123 - 138 (1996)
Update date:2022-07-30
Topics:
Evans, P. Andrew
Holmes, Andrew B.
McGeary, Ross P.
Nadin, Alan
Russell, Keith
O'Hanlon, Peter J.
Pearson, Neil D.
Unsaturated 8-, 9- and 10-membered medium ring lactams 1 (n = 1, 2, 3) have been prepared in good yield by the Claisen rearrangement of the vinyl-substituted precursors 3 in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU).
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