2-[(Alkylsulfonyl)oxy]-6-substituted-1H-isoindole-1,3(2H)-dione mechanism-based inhibitors of human leukocyte elastase

DOI: 10.1016/0960-894X(96)00038-8

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 451 - 456 (1996)

Update date:2022-07-30

Topics:

Authors:

Kerrigan, John E.

Shirley, Jennifer J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0960-894X(96)00038-8

Derivatives of 2-[(alkylsulfonyl)oxy]-1H-isoindole-1,3(2H)-diones (N-sulfonyloxy)phthalimides) with ring substituents in the 6-position were found to exhibit enhanced inhibitory potency and selectivity for HLE. The most potent inhibitor of HLE in this ser

Full text of DOI:10.1016/0960-894X(96)00038-8

Products guided by the article

Product name:2-N-(benzyl)oxy-5-nitroisoindole-1,3-dione

Cas No:175878-36-1

R&D Labs maybe for 175878-36-1

HANGZHOU YUNUO CHEMICAL CO.,LTD

website:http://www.yunuochem.com

Contact:0571-83715115

Address:hangzhou
Sinoway International (Jiangsu) Co., Ltd.

Contact:+86-25-86630167

Address:17 Beijing Road (West), Nanjing, China
Synasia Inc

Contact:17316303296

Address:240 Amboy Ave
KINHENG CHEMICAL(SHANGHAI)CO., LTD.

Contact:+8621-60490170

Address:Room401, No.28,Lane 189, Yangshupu Rd. Shanghai, China.
Nanjing Norris Pharm Technology Co., Ltd.

Contact:+86-13901585132

Address:2 Qiande Road, Jiangning sciencepark Hi-Tech Zone, Nanjing, P.R.China

Relevant to this article

Interaction of Z-1,2-borylphosphinoalkene with ketenimine

Doi:10.1007/BF01433757
(1996)
First synthetic method for the preparation of 6-unsubstituted-2,3-dihydro-1,3-oxazin-4-ones

Doi:10.1021/jo952118h
(1996)
Control of stereoselectivity in the ring-opening metathesis polymerization of norbornene by the auxiliary ligands butadiene and o-xylylene in well-defined pentamethylcyclopentadiene tantalum carbene complexes

Doi:10.1021/om9802966
(1998)
A new procedure for the isomerisation of substituted and unsubstituted allyl ethers of carbohydrates

Doi:10.1039/cc9960000141
(1996)
Substituted tetrahydropyrrolo[2,1-b]oxazol-5(6H)-ones and tetrahydropyrrolo[2,1-b]thiazol-5(6H)-ones as hypoglycemic agents

Doi:10.1021/jm9803121
(1998)
An alternative role for acetylenes: Activation of fluorobenzenes toward nucleophilic aromatic substitution

Doi:10.1021/jo400668v
(2013)

Article Doi