Tetrahedron p. 11087 - 11098 (1997)
Update date:2022-08-03
Topics:
Hoemann, Michael Z.
Agrios, Konstantinos A.
Aube, Jeffrey
The total synthesis of curacin A, a cytotoxic agent that interacts with the colchicine binding site on tubulin, is described. The convergent synthesis utilizes natural product and chiral pool starting materials (geraniol, serine) and asymmetric synthesis
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