Tetrahedron Letters p. 953 - 956 (1996)
Update date:2022-08-04
Topics:
Hoemann, Michael Z.
Agrios, Konstantinos A.
Aube, Jeffrey
Curacin A (1) was synthesized in a convergent manner. The key steps were (1) a Julia coupling to establish the stereochemistry of the C(7-10) diene, (2) a Wittig reaction to establish the stereochemistry of the C(3-4) alkene, and (3) a dehydrative cyclization to form the thiazoline ring system.
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