Cycloaromatization of enediyne model compounds via a reaction cascade triggered by hydrolysis of the α-alkynylmalonates

Article abstract of DOI:10.1016/0040-4039(95)02285-6

Diethyl α-methoxy-α-alkynylmalotate derivatives of cis-enediynes were synthesized and they produced toluenebiradicals via the reaction cascade triggered by ester hydrolysis. Deuterium labeling studies suggested that the reaction involved the self quenchin