A synthesis of novel 1H-imidazo[1,2-a]indole-3-carboxylates

Article abstract of DOI:10.1080/00397919608086749

A route to the uncommon imidazo[1,2-a]indole nucleus 1 is described via functionalisation and annelation of readily accessible 2-amino-indole-3-carboxylates 5. Intramolecular cyclization of a key-indolylformamidate 6 was utilised for the preparation of the 3,9-diester intermediates 7.

Full text of DOI:10.1080/00397919608086749

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Synthetic Communications: An
International Journal for Rapid
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Organic Chemistry
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A Synthesis of novel IH-
Imidazo[1,2-α]Indole-3-
Carboxylates
Ian T. Forbes a , Helen K.A. Morgan a & Mervyn
Thompson a
a SmithKline Beecham Pharmaceuticals , New
Frontiers Science Park, Third Avenue, Harlow, Essex,
CM 19 5 AW, UK
Published online: 21 Nov 2007.
To cite this article: Ian T. Forbes , Helen K.A. Morgan & Mervyn Thompson
(1996) A Synthesis of novel IH-Imidazo[1,2-α]Indole-3-Carboxylates, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 26:4, 745-754, DOI: 10.1080/00397919608086749
To link to this article: http://dx.doi.org/10.1080/00397919608086749
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