Bioorganic and Medicinal Chemistry Letters p. 393 - 396 (1996)
Update date:2022-08-05
Topics:
Casara
Ganzhorn
Philippo
Chanal
Danzin
Several unsaturated thioacetic acids were synthesized as potential mechanism-based inhibitors of peptidylglycine α-hydroxylating monooxygenase (PHM) prepared from horse serum. Trans-styrylthioacetic acid produced potent time-dependent inhibition of PHM. Potential mechanisms are proposed to explain PHM inactivation by unsaturated thioacetic acids.
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Doi:10.1055/s-1996-4192
(1996)Doi:10.1016/0040-4039(96)00056-1
(1996)Doi:10.1016/0040-4039(96)00049-4
(1996)Doi:10.1039/p19960000529
(1996)Doi:10.1016/0223-5234(96)80371-0
(1996)Doi:10.1002/anie.200701455
(2007)
