A new stereoselective route to (2S, 3S, 8S, 9S, 4E, 6E)-3-amino-9-methoxy-2, 6, 8-trimethyl-10-phenyldeca-4, 6-dienoic acid (Adda)

DOI: 10.1016/0040-4039(96)00282-1

Source and publish data:

Tetrahedron Letters p. 2349 - 2352 (1996)

Update date:2022-07-29

Topics:

Authors:

Kim, Hong Yong

Toogood, Peter L.

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Article abstract of DOI:10.1016/0040-4039(96)00282-1

N-Boc-Adda has been prepared in 15 steps and 9% overall yield from the readily available alcohol, 3-pentyne-2-ol, employing a route that includes two Claisen rearrangements.

Full text of DOI:10.1016/0040-4039(96)00282-1

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