Synthesis of enantiopure 3-hydroxymethylchromanes via intramolecular nitrone cycloaddition

DOI: 10.1016/0957-4166(96)00076-6

Source and publish data:

Tetrahedron Asymmetry p. 797 - 806 (1996)

Update date:2022-08-04

Topics:

Authors:

Broggini, Gianluigi

Folcio, Franco

Sardone, Nicola

Sonzogni, Milko

Zecchi, Gaetano

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Article abstract of DOI:10.1016/0957-4166(96)00076-6

Enantiopure (R) and (S) 3-hydroxymethylchromanes were prepared by the intramolecular nitrone cycloaddition strategy, starting from allyl-type ethers of 2-hydroxybenzaldehydes and using (R)-N-(α-phenylethyl)hydroxylamine as chiral auxiliary.

Full text of DOI:10.1016/0957-4166(96)00076-6

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