Synthesis and effects on arginase and nitric oxide synthase of two novel analogues of Nω-hydroxyarginine, Nω-hydroxyindospicine and p-hydroxyamidinophenylalanine

DOI: 10.1039/P19960000645

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 645 - 648 (1996)

Update date:2022-08-04

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Authors:

Vadon, Sandrine

Custot, Julien

Boucher, Jean-Luc

Mansuy, Daniel

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Article abstract of DOI:10.1039/P19960000645

Two novel amino adds, N^ω-hydroxy-D,L-indospicine and p-hydroxyamidino-D.L-phenylalanine, have been synthesized in four steps from tert-butoxycarbonylglycine. Both compounds act as good inhibitors of arginase, N^ω-hydroxyindospicine be

Full text of DOI:10.1039/P19960000645

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