Synthesis and alkylation of cyclopentane β-ketoxime sulfones. α,α-methylation-alkynylation of cyclopentanone

Article abstract of DOI:10.1016/0040-4020(96)00325-0

The synthesis and selected transformations of some cyclopentanoid β-ketoxime sulfone derivatives are reported. Utilization of the sulfone group to stabilize adjacent negative charge facilitates smooth alkylation. Subsequent 1,4-elimination of the sulfonyl