Catalyst control in a chiral borane-mediated aldol reaction. Both syn- and anti-aldols in almost optically pure state obtained from one racemic aldehyde

Article abstract of DOI:10.1016/0040-4039(96)00379-6

Chiral borane (L-2 and D-2)-mediated aldol reaction proceeded with chiral aldehydes (1, 5, and 9) in a manner of 'catalyst control'. Both enantiomers were obtained from one racemic aldehyde in almost optically pure state.