A convenient preparation of elements of the stereotriade

Article abstract of DOI:10.1016/0040-4039(96)00417-0

Enzyme-catalysed acetylation of either syn,syn- or anti,anti-2,4-dimethyl-1,3,5-pentane triol, easily obtained from a mixture of diastereomeric 3-hydroxy-2,4-dimethylglutaric acids, proceeds stereoselectively with preferential attack of the hydromethyl group linked to the R carbon atom of the starting triol, hence providing synthons useful for preparing compounds of the polypropionic pool.