Serine derived NK1 antagonists 1: The effect of modifications to the serine substituents

DOI: 10.1016/S0960-894X(98)00320-5

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1845 - 1850 (1998)

Update date:2022-07-31

Topics:

Authors:

Elliott Elliott

Cascieri

Chicchi Chicchi

Davies Davies

Kelleher

Kurtz Kurtz

Ladduwahetty

Lewis Lewis

MacLeod MacLeod

Merchant

Sadowski

Stevenson

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Article abstract of DOI:10.1016/S0960-894X(98)00320-5

A series of novel serine derived NK₁ antagonists is described. The effect of variations in the N-benzyl, O-benzyl and serine groups are used to define the elements which are necessary for binding.

Full text of DOI:10.1016/S0960-894X(98)00320-5

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