Serine derived NK1 antagonists 1: The effect of modifications to the serine substituents

DOI: 10.1016/S0960-894X(98)00320-5

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 1845 - 1850 (1998)

Update date:2022-07-31

Topics:

Authors:

Elliott Elliott

Cascieri

Chicchi Chicchi

Davies Davies

Kelleher

Kurtz Kurtz

Ladduwahetty

Lewis Lewis

MacLeod MacLeod

Merchant

Sadowski

Stevenson

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(98)00320-5

A series of novel serine derived NK₁ antagonists is described. The effect of variations in the N-benzyl, O-benzyl and serine groups are used to define the elements which are necessary for binding.

Full text of DOI:10.1016/S0960-894X(98)00320-5

Products guided by the article

Product name:5-(3,4-Dichloro-phenyl)-2-oxo-pentanoic acid ethyl ester

Cas No:178261-37-5

R&D Labs maybe for 178261-37-5

Zhenjiang Huayu I/E Co.,LTD

Contact:86-511-85210668 0511-85210668, 85210818, 85210898

Address:Yihai Garden E-902,NO.99 Daxi RD., Zhenjiang Jiiangsu ,China
SHAANXI FUJIE PHARMACEUTICAL CO.,LTD

website:http://www.fujiepharm.com

Contact:+86-29-63650906

Address:Yuanqu Yi Road, Qinghe Food Industrial Park, Sanyuan County, Shaanxi Province, China
Hunan Haili Chemical Industry Co.,Ltd.

Contact:+86-731-85521860

Address:No.251, 2nd Section, Furong Road, Changsha,Hunan,China
SHENZHEN PENGCHENG REDSTAR INDUSTRY CO.,LTD

Contact:+86-755-82412922

Address:Room 8066, East Block, Square City, Jiabin Road, Luohu District
Linyi VIHO Chemical Co.,Ltd

Contact:86-15588110016

Address:LINYI CITY,SHANDONG PROVINCE,CHINA

Relevant to this article

Sila- and Germacarboxylic Acids: Precursors for the Corresponding Silyl and Germyl Radicals

Doi:10.1002/anie.202003070
(2020)
Magnesium nitride as a convenient source of ammonia: Preparation of primary amides

Doi:10.1021/ol801398z
(2008)
Synthesis and antioxidant activities of novel 4-Schiff base-7-benzyloxy- coumarin derivatives

Doi:10.1016/j.bmcl.2011.09.029
(2011)
Facile preparation of cyclopropanes from 2-iodoethyl-substituted olefins and 1,3-dihalopropanes with zinc powder

Doi:10.1016/j.tet.2005.07.103
(2005)
Synthesis and reactivity of 3-(benzothiazol-2-yl)-3-oxopropanenitrile

Doi:10.1016/0040-4020(96)00360-2
(1996)
Synthesis of highly substituted imidazolidine-2,4-dione (Hydantoin) through Tf₂O-mediated dual activation of Boc-protected dipeptidyl compounds

Doi:10.1021/ol502900j
(2014)

Article Doi