Bioorganic and Medicinal Chemistry Letters p. 1845 - 1850 (1998)
Update date:2022-07-31
Topics:
Elliott
Cascieri
Chicchi
Davies
Kelleher
Kurtz
Ladduwahetty
Lewis
MacLeod
Merchant
Sadowski
Stevenson
A series of novel serine derived NK1 antagonists is described. The effect of variations in the N-benzyl, O-benzyl and serine groups are used to define the elements which are necessary for binding.
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