Journal of Heterocyclic Chemistry p. 475 - 478 (1996)
Update date:2022-08-02
Topics:
Malamas, Michael S.
Palka, Cynthia L.
A new synthesis of 5-substituted isoxazolidines was developed by direct isoxazolidine ring formation of allylic hydroxylamines under acidic conditions. The cyclization process is an electrophilic SN1 type reaction. The formed carbocation intermediate is stabilized by electron rich groups (i.e., phenyl). A moiety that mediates oxonium ion formation (i.e., para-methoxy) accelerates the rate of product formation.
View MoreContact:0571-
Address:zhejing
Shenyang Xingzhenghe Chemical Co., Ltd.
Contact:024-23509232
Address:No. 33, Naner Road, Heping Dist.
Contact:+86-371-55981030
Address:Room 1571, Macalline Soho, No.1, Shangdu Road, Zhengzhou, Henan
Luojiang Chenming Biological Products Co
Contact:+86 15000297032
Address:GROUP NO.4, HE SHENG VILLAGE, PANLONG TOWN,
Shenzhen HwaGen Pharmaceutical Co., Ltd
website:http://www.rafflespt.com
Contact:+86-752-5538396
Address:Guangdong Huizhou China
Doi:10.1021/jo960203z
(1996)Doi:10.1016/S0022-328X(00)85682-X
(1975)Doi:10.1007/BF02895111
(1954)Doi:10.1021/jm960594+
(1997)Doi:10.1016/j.catcom.2016.08.018
(2016)Doi:10.1016/S0040-4020(00)00650-5
(2000)
