Molecular basis of peripheral vs central benzodiazepine receptor selectivity in a new class of peripheral benzodiazepine receptor ligands related to alpidem

DOI: 10.1021/jm960325j

Source and publish data:

Journal of Medicinal Chemistry p. 4275 - 4284 (1996)

Update date:2022-07-31

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Authors:

Anzini, Maurizio

Cappelli, Andrea

Vomero, Salvatore

Giorgi, Gianluca

Langer, Thierry

Bruni, Giancarlo

Romeo, Maria R.

Basile, Anthony S.

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Article abstract of DOI:10.1021/jm960325j

Alpidem (1), the anxiolytic imidazopyridine, has nanomolar binding affinity for both the central benzodiazepine receptor (cbr) and the peripheral benzodiazepine receptor (pbr). A novel class of pbr ligands related to alpidem has been designed by comparing

Full text of DOI:10.1021/jm960325j

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