Helvetica Chimica Acta p. 961 - 972 (1996)
Update date:2022-08-05
Topics:
Misun, Marian
Pfaltz, Andreas
'Semicorrin' cobalt complexes, prepared in situ from cobalt(II) chloride and the corresponding ligands, are efficient catalysts for the enantioselective reduction of electrophilic C=C bonds with NaBH4. The best selectivities (> 90% ee) are achieved with α,β-unsaturated carboxamides and carboxylates. Analogous α,β-unsaturated nitriles, sulfones, and phosphonates afford enantiomenc excesses of 50-70%. Interestingly, in the reduction of α,β-unsaturated sulfones, the highest enantioselectivities were obtained with unsymmetrical 'semicorrins', whereas in all other cases C2-symmetric 'semicorrins' proved to be superior.
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Doi:10.1246/bcsj.69.1705
(1996)Doi:10.1039/d1ob01002f
(2021)Doi:10.1016/0040-4039(96)01209-9
(1996)Doi:10.1007/BF02674051
(1955)Doi:10.1016/0960-894X(96)00296-X
(1996)Doi:10.1016/0040-4020(96)00542-X
(1996)