
Tetrahedron Asymmetry p. 1723 - 1732 (1996)
Update date:2022-08-03
Topics:
Warmerdam, Erwin G.J.C.
Van Rijn, Rachel D.
Brussee, Johannes
Kruse, Chris G.
Van Der Gen, Arne
(-)-(R,E)-2-hydroxy-3-pentenenitrile 1, obtained by R-oxynitrilase catalyzed addition of HCN to 2-butenal, was shown to be an excellent chiral starting material for the synthesis of α-hydroxy-β-amino acids of high enantiomeric and diastereomeric purity. T
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Doi:10.1246/bcsj.40.2930
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(1996)