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Synthesis of α-hydroxy-β-amino acids from chiral cyanohydrins

DOI: 10.1016/0957-4166(96)00206-6

Source and publish data:

Tetrahedron Asymmetry p. 1723 - 1732 (1996)

Update date:2022-08-03

Topics:

Authors:

Warmerdam, Erwin G.J.C.Warmerdam, Erwin G.J.C.

Van Rijn, Rachel D.Van Rijn, Rachel D.

Brussee, JohannesBrussee, Johannes

Kruse, Chris G.Kruse, Chris G.

Van Der Gen, ArneVan Der Gen, Arne

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Article abstract of DOI:10.1016/0957-4166(96)00206-6

(-)-(R,E)-2-hydroxy-3-pentenenitrile 1, obtained by R-oxynitrilase catalyzed addition of HCN to 2-butenal, was shown to be an excellent chiral starting material for the synthesis of α-hydroxy-β-amino acids of high enantiomeric and diastereomeric purity. T

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Full text of DOI:10.1016/0957-4166(96)00206-6

Products guided by the article

Product name:Benzyl-[(E)-(1S,2R)-2-(tert-butyl-dimethyl-silanyloxy)-1-methyl-pent-3-enyl]-amine

Cas No:180718-52-9

180718-52-9

R&D Labs maybe for 180718-52-9

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