Tetrahedron Asymmetry p. 3119 - 3128 (1996)
Update date:2022-08-03
Topics:
Kovensky, Jose
Duchaussoy, Philippe
Petitou, Maurice
Sinay, Pierre
The total chemical synthesis of the pentasaccharide methyl O-(α-L-idopyranosyluronic acid)-(1 → 4)-O-(2-deoxy-2-sulfamido-α-D-glucopyranosyl)-(1 → 4)-O-(α-L-idopyranosyluronic acid)-(1 → 4)-O-(2-deoxy-2-sulfamido-α-D-glycopyranosyl)-(1 → 4)-2-O-sulfo-α-L-idopyranosiduronic acid is reported. This sequence is a possible candidate for binding to basic fibroblast growth factor (FGF-2) (J. Biol. Chem., 1993, 268, 23898-23905). Copyright (C) 1996 Published by Elsevier Science Ltd.
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Doi:10.1016/S0040-4039(01)97975-4
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(1996)
