Bioorganic and Medicinal Chemistry Letters p. 1875 - 1880 (1996)
Update date:2022-08-02
Topics:
Ohba, Tsuyoshi
Ikeda, Eitatsu
Takei, Hisashi
Fluorinated phenylalanine analogues were found to be slow-binding or reversible competitive inhibitors of α-chymotrypsin. A series of these compounds were designed to inactivate α-chymotrypsin as a result of the formation of hydrogen-bonding between fluorine atom of the inhibitors and the amide protons known as oxy-anion hole in the active-site of serine and cysteine proteases.
View MoreZhejiang Sanmei Chemical Industry Co., Ltd
Contact:86-579-87633213
Address:Huchu Industrial Zone, Qingnian Rd., Wuyi County, Zhejiang Prov., China.
Contact:+86-021-58123769
Address:No.780 of Cailun Road,Zhangjiang Hi-tech Park,Pudong,Shanghai
Wuhan Kemi-Works Chemical Co., Ltd
website:http://www.kemiworks.com
Contact:86-27-85736489
Address:Rm. 1503, No. 164, Jianghan North Rd., Wuhan, 430022 China
website:http://www.finerchem.com
Contact:+86-531-88989536
Address:New Material Industry Park, Jinan Ciyt, China
Nanjing Samwon International Limited
Contact:+86-25-84873444
Address:1108, BLDG B, New Century Plaza, No 1, South Taiping Rd.,
Doi:10.1080/10426509708044216
(1997)Doi:10.1016/0040-4039(96)01121-5
(1996)Doi:10.1016/0022-328X(91)86347-S
(1991)Doi:10.1016/j.bmcl.2018.06.015
(2018)Doi:10.1039/p19960001683
(1996)Doi:10.1023/A:1022674318345
(2002)
