
Chemistry Letters p. 175 - 178 (1984)
Update date:2022-08-06
Topics:
Nishizawa, Makoto
Kurihara, Takashi
Hata, Tsujiaki
Cyclic phosphorodianilidate derivatives of nucleoside 5'-phosphates were prepared by use of triphenylphosphine and 2,2'-dipyridyl disulfide as condensing agent and used for the synthesis of oligodeoxyribonucleotides.Removal of the diamino group was remarkably accelerated by coaddition of AgOAc and acid anhydrides to the conventional system, iAmONO-pyridine-AcOH.
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