Synthetic Communications p. 3733 - 3755 (1996)
Update date:2022-07-30
Topics:
Hozien
Atta
Hassan
Abdel-Wahab
Ahmed
The paper describes the synthesis of a new ring system 5-phenylthieno[2,3-d]pyrimidine-4(3H)one (2). Chlorination of (2) with PCl5, POCl3 gave the corresponding 4-chloro derivative (4). Several derivatives of the latter compound have been synthesised and tested for antimicrobial activity.
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Doi:10.1002/jps.2600570433
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