Enantioselective Michael reaction of ketone lithium enolates using a chiral ligand

DOI: 10.1016/0040-4039(96)01367-6

Source and publish data:

Tetrahedron Letters p. 6343 - 6346 (1996)

Update date:2022-08-03

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Authors:

Yasuda, Kosuke

Shindo, Mitsuru

Koga, Kenji

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Article abstract of DOI:10.1016/0040-4039(96)01367-6

The enantioselective Michael reaction of ketone lithium enolates using a chiral amine ligand (1) was studied. Michael adducts (4) of up to 94% ee were obtained by the reaction between methyl ketones (2) and Michael acceptors (3) having a benzylidene group.

Full text of DOI:10.1016/0040-4039(96)01367-6

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