Exploitation of highly functionalised epoxides derived from asymmetrized tris(hydroxymethyl)methane (THYM*) in the synthesis of a fragment of lasalocide A and other related polyether ionofore antibiotics

DOI: 10.1016/0040-4020(96)00751-X

Source and publish data:

Tetrahedron p. 12631 - 12642 (1996)

Update date:2022-09-26

Topics:

Authors:

Guanti, Giuseppe

Narisano, Enrica

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Article abstract of DOI:10.1016/0040-4020(96)00751-X

A fragment for the total convergent synthesis of some polyether ionophore antibiotics (lasalocide A, isolasalocide A, lysocellin) has been obtained through 'higher order' vinyl cuprate ring opening of functionalised epoxides derived from THYM*.

Full text of DOI:10.1016/0040-4020(96)00751-X

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