MOM-protected 3-hydroxy-5-phenyl-isoxazole: Regioselective preparation and synthetic application

DOI: 10.1016/0040-4039(96)01547-X

Source and publish data:

Tetrahedron Letters p. 6857 - 6860 (1996)

Update date:2022-09-26

Topics:

Authors:

Alzeer, Jawad

Nock, Nadine

Wassner, Guy

Masciadri, Raffaello

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(96)01547-X

Highly regioselective (> 90%) MOM-protection of 3-hydroxy-5-phenyl-isoxazole, followed by elaboration in 4-position via directed ortho-metalation and mild deprotection with cold methanolic HCl provided ready access to a series of zwitterionic isoxazole derivatives.

Full text of DOI:10.1016/0040-4039(96)01547-X

Products guided by the article

Product name:3-Methoxymethoxy-5-phenyl-isoxazole-4-carbaldehyde

Cas No:183284-36-8

R&D Labs maybe for 183284-36-8

Shangyu Sanhechemicals Co.,LTD.

Contact:86-0571-56696839

Address:Num.2952,Nanhuan Road,Binjiang District,Hangzhou,China
Improve Medical Technology(Nanxiong) Co., Ltd

Contact:86-751-3836997

Address:No.33, Pingan First Road, Fine Chemical Industry Base, Nanxiong City, Shaoguan, Guangdong, China
Xinjiang Zhongtai Chemical Co., Ltd.

Contact:+86-991-8788172

Address:NO.78 XISHAN RD.URUMQI，CHINA
Landz International Company Ltd.

Contact:0086-21-58891610

Address:985 Dongfang Road, Pudong, Shanghai 200122 China
Wuhan Silworld Chemical Co.,Ltd

website:http://www.silworldchemical.com

Contact:+86-27-85613400

Address:No.198 jiangjun Road, Wuhan,China 430033

Relevant to this article

2'-Deoxy-2'-alkoxyaminouridines: Novel 2'-substituted uridines prepared by intramolecular nucleophilic ring opening of 2,2'-O-anhydrouridines

Doi:10.1016/0040-4020(96)00870-8
(1996)
trans-Chloromethylbis(dimethyl sulfoxide)platinum(II): X-ray Structure, Mechanism of Isomerization, and Its Use as a Precursor to Organoamine Complexes of Variable Geometrical Configurations

Doi:10.1021/ic960428s
(1996)
Doi:10.1080/10426509608037952
(1996)
Solvatothermal synthesis and crystal structure of (Ph₄P)[(VO₂)₄(CH₃CO ₂)₄cl]

Doi:10.1016/s0020-1693(96)05325-x
(1996)
Cholecystokinin B antagonists. Synthesis and quantitative structure-activity relationships of a series of C-terminal analogues of CI-988

Doi:10.1016/0968-0896(96)00185-X
(1996)
Doi:10.1021/ja00996a029
(1967)

Article Doi