MOM-protected 3-hydroxy-5-phenyl-isoxazole: Regioselective preparation and synthetic application

DOI: 10.1016/0040-4039(96)01547-X

Source and publish data:

Tetrahedron Letters p. 6857 - 6860 (1996)

Update date:2022-09-26

Topics:

Authors:

Alzeer, Jawad

Nock, Nadine

Wassner, Guy

Masciadri, Raffaello

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0040-4039(96)01547-X

Highly regioselective (> 90%) MOM-protection of 3-hydroxy-5-phenyl-isoxazole, followed by elaboration in 4-position via directed ortho-metalation and mild deprotection with cold methanolic HCl provided ready access to a series of zwitterionic isoxazole derivatives.

Full text of DOI:10.1016/0040-4039(96)01547-X

Products guided by the article

Product name:3-Methoxymethoxy-5-phenyl-isoxazole-4-carbaldehyde

Cas No:183284-36-8

R&D Labs maybe for 183284-36-8

Shandong Bolode Bio-Technology Co., LTD

Contact:+86-0531-58966870

Address:136 Jingyi Road,Huaiyin District,Jinan,Shandong,China
Hebei Fulong Import & Export Co., Ltd.

Contact:86-311-87795661

Address:15A19 Zhongyuan Building,368 Youyi North Street,Shijiazhuang 050070,China
Shenzhen JYMed Technology Co.,Ltd.

website:http://www.jymedtech.com

Contact:+86-755-26612112

Address:1#8,9/F, Biomedicine innovation Industrial Park, No.14, Jinhui Road, Pingshan Sistrict, Shenzhen, China
Puyang Willing Chemicals Co.,Ltd.

Contact:86-393-4840366

Address:Puyang Henan China
Beijing Ribio Biotech Co.,Ltd

Contact:86-10-62664360

Address:Building 10,No.18 AnNingZhuang East Road, GuangHua Pioneer Park,HaiDian District, BeiJing China

Relevant to this article

2'-Deoxy-2'-alkoxyaminouridines: Novel 2'-substituted uridines prepared by intramolecular nucleophilic ring opening of 2,2'-O-anhydrouridines

Doi:10.1016/0040-4020(96)00870-8
(1996)
trans-Chloromethylbis(dimethyl sulfoxide)platinum(II): X-ray Structure, Mechanism of Isomerization, and Its Use as a Precursor to Organoamine Complexes of Variable Geometrical Configurations

Doi:10.1021/ic960428s
(1996)
Doi:10.1080/10426509608037952
(1996)
Solvatothermal synthesis and crystal structure of (Ph₄P)[(VO₂)₄(CH₃CO ₂)₄cl]

Doi:10.1016/s0020-1693(96)05325-x
(1996)
Cholecystokinin B antagonists. Synthesis and quantitative structure-activity relationships of a series of C-terminal analogues of CI-988

Doi:10.1016/0968-0896(96)00185-X
(1996)
Doi:10.1021/ja00996a029
(1967)

Article Doi