Synthesis of chiral triamines and diamines from amino acids

Article abstract of DOI:10.1055/s-1996-4358

Selectively protected (2S)-1,2,6-triaminohexane 4 was prepared from L-lysine by reduction of the amino acid, replacement of the hydroxy group by an azido group and selective reduction. Following the same method vicinal diamines 11 and 13 bearing a third functional group were synthesized from L-glutamic acid.