Design, synthesis, resolution, and application of a highly efficient chiral auxiliary: cis-2-amino-3,3-dimethyl-1-indanol

DOI: 10.1016/0957-4166(96)00385-0

Source and publish data:

Tetrahedron Asymmetry p. 2939 - 2956 (1996)

Update date:2022-08-05

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Authors:

Sudo, Atsushi

Saigo, Kazuhiko

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Article abstract of DOI:10.1016/0957-4166(96)00385-0

The chiral amino alcohol, cis-2-amino-3,3-dimethyl-1-indanol was synthesized and resolved. Its oxazolidinone derivative was found to be a highly efficient chiral auxiliary in diastereoselective alkylation, acylation, bromination, and hydroxylation reactions.

Full text of DOI:10.1016/0957-4166(96)00385-0

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