Heterocyclic Communications p. 427 - 432 (2002)
Update date:2022-08-02
Topics:
Azevedo, Alexandre R.
Ferreira, Vitor F.
De Mello, Heloisa
Leao-Ferreira, Luiz R.
Jabor, Alfredo V.
Frugulhetti, Izabel C. P. P.
Pereira, Helena S.
Moussatche, Nissin
Bernardino, Alice M. Rolim
Several new 3-phenyl and 3-alkyl-1H-pyrazolo[3,4-b]pyridine derivatives (3a-e) were prepared and evaluated against Vaccinia virus on BSC-40 cells. The derivatives 3a, 3b and 3d showed an inhibitory activity above 90% at 30 μM, 40 μM and 50 μM concentrations.
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