Synthesis and Biological Evaluation of New Fused Thiazolo[4,5-d] Pyridazine Derivatives

Article abstract of DOI:10.1002/jccs.199600062

The synthesis of thiazolo[4,5-d]pyridazines and the unknown ring systems, thiazolo[4,5-d]-l,2,4-triazolo- and tetrazolo[4,3-b]pyridazines as well as thiazolo[4,5-d]pyridazino[2,3-c]2H triazines, has been achieved according to different pathways. Biological testing of the new tricyclic heterocycles revealed that some of these compounds possess remarkable antibacterial activity.