Preparation and absolute configurations of optical isomers of sodium 2- [[4-(3-methoxypropoxy)-3-methylpyridin-2-yl] methylsulfinyl]-1H-benzimidazole (E3810)

DOI: 10.1248/cpb.44.1853

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1853 - 1857 (1996)

Update date:2022-08-03

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Authors:

Nochi, Shigeharu

Kawai, Takatoshi

Kawakami, Yoshiyuki

Asakawa, Naoki

Ueda, Norihiro

Hayashi, Kenji

Souda, Shigeru

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Article abstract of DOI:10.1248/cpb.44.1853

The optical isomers of sodium 2-[[4-(3-methoxypropoxy)-3-methylpyridin- 2-yl]methylsulfinyl]-1H-benzimidazole (E3810), a proton pump inhibitor, were separated by HPLC and their absolute configurations were determined by X-ray crystallographic analysis.

Full text of DOI:10.1248/cpb.44.1853

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