Tetrahedron Letters p. 7929 - 7932 (1996)
Update date:2022-09-26
Topics:
Claffey, David J.
Ruth, James A.
The four possible stereoisomers of 3,4-epoxybutane-1,2-diol were stereospecifically synthesized in excellent yields, and fully characterized, as part of a study on the stereochemical aspects of butadiene metabolism and toxicity. GC methodology was developed whereby baseline separation of the enantiomeric pairs was achieved.
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