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Exclusive affinity-labeling of μ opioid receptors by morphiceptin analogs containing S-(3-nitro-2-pyridylthio)cysteine

DOI: 10.1246/bcsj.69.3607

Source and publish data:

Bulletin of the Chemical Society of Japan p. 3607 - 3612 (1996)

Update date:2022-08-04

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Authors:

Motoyama, ShihokoMotoyama, Shihoko

Takada, KiyoshiTakada, Kiyoshi

Yasunaga, TeruoYasunaga, Teruo

Fujita, TsugumiFujita, Tsugumi

Shimohigashi, YasuyukiShimohigashi, Yasuyuki

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Article abstract of DOI:10.1246/bcsj.69.3607

The S-(3-nitro-2-pyridylthio) (Npys) group only reacts with a free mercapto group to form a disulfide bond. A series of morphiceptin analogs containing SNpys-cysteine were designed and synthesized for specific affinity-labeling of μ opioid receptors. Affi

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Full text of DOI:10.1246/bcsj.69.3607

Products guided by the article

Product name:[(R)-2-((S)-2-Carbamoyl-pyrrolidin-1-yl)-1-(4-methoxy-benzylsulfanylmethyl)-2-oxo-ethyl]-carbamic acid tert-butyl ester

Cas No:185141-47-3

185141-47-3

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