Methidium intercalator inserted into synthetic oligonucleotides

DOI: 10.1016/0040-4039(96)01968-5

Source and publish data:

Tetrahedron Letters p. 8467 - 8470 (1996)

Update date:2022-07-30

Topics:

Authors:

Timofeev, Edward N.

Smirnov, Igor P.

Haff, Lawrence A.

Tishchenko, Ekaterina I.

Mirzabekov, Andrei D.

Florentiev, Vladimir L.

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Article abstract of DOI:10.1016/0040-4039(96)01968-5

A new methidium intercalator phosphoramidite has been synthesized. Methidium incorporation into an oligonucleotide during the synthesis was confirmed by UV and MALDI TOF MS data. UV melting experiments showed enhanced stability of a duplex, containing internal methidium.

Full text of DOI:10.1016/0040-4039(96)01968-5

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