Bioorganic and Medicinal Chemistry Letters p. 1157 - 1162 (1998)
Update date:2022-08-05
Topics:
Campbell, David A.
Xiao, Xiao-Yi
Harris, David
Ida, Satoru
Mortezaei, Reza
Ngu, Khehyong
Shi, Lihong
Tien, David
Wang, Yongwen
Navre, Marc
Patel, Dinesh V.
Sharr, Michele A.
DiJoseph, John F.
Killar, Loran M.
Leone, Christina L.
Levin, Jeremy I.
Skotnicki, Jerauld S.
A novel series of matrix metalloproteinase (MMP) inhibitors is described. Incorporation of a terminal α-mercaptoketone or α- mercaptoalcohol in the zinc binding domain of a series of inhibitors led to compounds exhibiting low nanomolar activity against collagenase-1 (MMP-1), stromelysin (MMP-3), and gelatinase-B (MMP-9).
View MoreOren Hydrocarbons (Qingdao) Co., Ltd.
Contact:+86-532-68607667-801
Address:Room 3 # 302, No.9 Qingyun Road, Qingdao, China
TAIXING BEST NEW MATERIALS CO., LTD
Contact:0523-87998158;
Address:No.18 Zhonggang Road，Taixing City ，Jiangsu , China
Contact:86+21-56421993
Address:3F,BUILDING 10,NO.2889 JINKE ROAD, SHANGHAI.
Suzhou Time-chem Technologies Co., Ltd.
Contact:0512-63983931/68086856
Address:No. 1326 of Binhe Road, New District, Suzhou, Jiangsu, P. R. China
website:http://www.shtopchem.com/
Contact:0086-0576-87776998
Address:room no 1608,xuhui business building yude road,xujiahui street, xuhui district
Doi:10.1111/cbdd.12319
(2014)Doi:10.1016/0022-328X(68)80072-5
(1968)Doi:10.1016/S0968-0896(96)00182-4
(1996)Doi:10.1039/a606575i
(1997)Doi:10.1021/jo962135m
(1997)Doi:10.1021/jo982154r
(1999)
