Nucleosides and nucleotides. 161. Incorporation of 5-(N-aminoalkyl)carbamoyl-2'-deoxycytidines into oligodeoxyribonucleotides by a convenient post-synthetic modification method

DOI: 10.1016/S0960-894X(96)00519-7

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2811 - 2816 (1996)

Update date:2022-08-03

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Authors:

Nomura, Yukari

Haginoya, Noriyasu

Ueno, Yoshihito

Matsuda, Akira

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Article abstract of DOI:10.1016/S0960-894X(96)00519-7

5-Trifluoroethoxycarbonyl-2'-deoxycytidine derivatives were synthesized and incorporated into oligonucleotides. The fully protected oligonucleotides were treated diaminoethane or 1,6-diaminohexane to give oligonucleotides carrying amino-linkers, which were further derivatized with an intercalator. The properties of these oligonucleotides are described.

Full text of DOI:10.1016/S0960-894X(96)00519-7

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