Tetrahedron Letters p. 9321 - 9324 (1996)
Update date:2022-08-04
Topics:
Masaki, Yukio
Yoshizawa, Kazuhiro
Itoh, Akichika
Optically active natural thromboxane B2 (TXB2) was synthesized from (R,R)-tartaric acid as only chiral source. The synthesis was achieved through regio- and stereoselective introduction of acetate moiety at the C2-position of the 6,8-dioxabicyclo[3.2.1]octene derivative (2) to provide an acetamide derivative (6), partial ring opening of 6 to give a pyranoid (10), and construction of the C15-hydroxyl group of TXB2 by stereospecific allylic transposition of the inherent chirality of tartaric acid in the transallylic acetate (18).
View MoreNanjing Chemlin Chemical Co., Ltd.
website:http://www.echemlin.cn
Contact:+86-25-83697070
Address:Rm.902 Longyin Plaza, No. 217 Zhongshan Rd.(N) Nanjing 210009,China
Hangzhou Eastbiopharm Co.,Ltd.
Contact:+86-571-88931780
Address:Hangzhou,China
Guilin Zhenda Bio-Tech Co., Ltd.
Contact:86-773-3568977
Address:-Yangtang shangshui industry park, Lingui county,
Contact:+44 7958 511245
Address:PO Box 469, Manchester, UK
Engineering Research Center of Pesticide, Heilongjiang Province
Contact:+86-451-86609001
Address:No.74 of Xuefu Road, Nangang District,
Doi:10.1021/jo970042e
(1997)Doi:10.1016/S0022-328X(00)82214-7
(1964)Doi:10.1021/jo961955w
(1997)Doi:10.1021/om9609168
(1997)Doi:10.1016/S0040-4039(96)02352-0
(1997)Doi:10.1039/a601642a
(1997)