Synthetic Communications p. 3183 - 3189 (2004)
Update date:2022-08-05
Topics:
Guo, Yuan
Shi, Zhen
A convenient synthetic method for the preparation of symmetric acyclic diketones from dicarboxylic acids is provided. Three bis-benzimidazolium salts were used as tetrahydrofolate coenzyme model, thus the biomimetic synthesis of three symmetric acyclic diketones was successfully accomplished by using the addition-hydrolysis reaction of corresponding bis-benzimidazolium salts with methyl magnesium iodide.
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