Heterocyclisation via 1,3-Cyclic Sulfates. Asymmetric Synthesis of (+)-Sedridine

Article abstract of DOI:10.1055/s-1997-699

1,3-Cyclic sulfates (1b-d) participate in heterocyclisation reactions to give pyrrolidines (2b) and piperidines (2c/d). Cyclic sulfate activation, when coupled to the enantio- and diastereoselective generation of 1,3-diols, provides a synthesis of (+)-sedridine (9).