Synthesis p. 1438 - 1442 (1996)
Update date:2022-08-02
Topics:
Enders
Bartsch
Backhaus
Runsink
Raabe
The diastereo- and enantioselective synthesis of β-substituted γ,δ-unsaturated cyclic α-hydroxy ketones 4 with neighboring quarternary and tertiary stereogenic centers via asymmetric [2,3]-Wittig rearrangement of SAEP-hydrazones 2 with good overall yields (58-74%), high anti-selectivities (92-94%) and excellent enantiomeric excesses (ee ≤ 96%) is described. The absolute configuration is determined by X-ray structure analysis of the hydrazone 3b and by 1H NMR NOE measurements.
View MoreShenzhen Sunrising Industry Co., ltd.
Contact:+86 755 86571158 / 86571159 / 86571160
Address:2108 ZHENYE INT. BUSINESS CENTER,NO.3101-90 QIANHAI RD, NANSHAN,SHENZHEN, CHINA
Anhui Dexinjia Biopharm Co., Ltd
Contact:+86-531-82375818
Address:9 Hexie Road, kaifaqu, Taihe
Shanghai Mio Chemical Co., Ltd
Contact:0086 21- 64401188-622
Address:16 Floor NO.2 Jiefang Building, No. 4855 Dushi Road, 201100 Shanghai, P.R.China
Beijing Greenchem Technology Co.,Ltd. ( Panjin Greenchem Technology Co.Ltd .)
website:http://www.bjgreenchem.com/
Contact:+86-427-6515887
Address:301,302, 3rd Floor, Building C-7, Dongsheng Science Park, Northern Territory, Zhongguancun, No. 66, Xixiaokou Road, Haidian District, Beijing
website:http://www.lidepharma.com
Contact:+86-25-58409506
Address:11F, Building A1, No.288 North Zhongshan Road, Gulou District, Nanjing,210003, P.R.China.
Doi:10.1016/j.tetlet.2007.04.058
(2007)Doi:10.1021/ja9635589
(1997)Doi:10.1007/BF01431345
(1996)Doi:10.1002/ejic.201201428
(2013)Doi:10.1002/jlac.199719970211
(1997)Doi:10.1002/adsc.201201125
(2013)