Angewandte Chemie - International Edition in English p. 166 - 168 (1997)
Update date:2022-08-03
Topics:
Yang
He
Vourloumis
Vallberg
Nicolau
A flexible alterative route to the total synthesis of the antitumor agent epothilone A has been achieved by a highly convergent strategy involving olefin metathesis as a key step. The strategy may allow the chemical synthesis of a library of designed epothilones for biological screening.
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Doi:10.1016/S0040-4039(96)02454-9
(1997)Doi:10.1002/hlca.19970800114
(1997)Doi:10.1021/jo01077a031
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(1997)Doi:10.1039/c5cc01345c
(2015)