Stereoselective access to trans-2,5-disubstituted pyrrolidine derivatives by nucleophilic addition to bicyclic N-acyliminium ion

DOI: 10.1016/S0040-4039(97)00099-3

Source and publish data:

Tetrahedron Letters p. 1415 - 1418 (1997)

Update date:2022-08-05

Topics:

Authors:

Dhimane, Hamid

Vanucci, Corinne

Lhommet, Gerard

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(97)00099-3

5-Alkoxy-pyrroloxazolidin-3-ones 1 were stereoselectively prepared from (S)-pyroglutamic acid. Treatment of 1 with a Lewis acid generated in situ the N-acyliminium 2, which was trapped by various π-nuclcophiles leading selectively to trans pyrrolidine derivatives 3.

Full text of DOI:10.1016/S0040-4039(97)00099-3

Products guided by the article

Product name:(S)-2-Methoxy-5-(toluene-4-sulfonyloxymethyl)-pyrrolidine-1-carboxylic acid tert-butyl ester

Cas No:188015-49-8

R&D Labs maybe for 188015-49-8

Aqua Chem Industry Co., Ltd

Contact:+86-515-88356562

Address:No.2, West Daqing Road, Yancheng, Jiangsu, China
Chemsky（shanghai）International Co.,Ltd.

Contact:0

Address:0
Jai Radhe Sales

website:http://www.jairadhesales.com

Contact:0091-79-26431096

Address:309 Harikrupa Tower,Nr old Sharda Mandir Char Rasta,Ellisbridge
HUNAN OUYA BIOLOGICAL CO.,LTD

Contact:+8613400661290

Address:No 908,Kangwan Rd, Liuyang Economic
Shanghai Balmxy Pharmaceutical Co., Ltd

Contact:0086-21-24206007

Address:Room 402, 15#, No. 909 wangyue Road, shanghai, P. R. China

Relevant to this article

Role of substrate reactivity in the glutathione peroxidase (gpx) activity of selenocystine

Doi:10.1246/bcsj.20090348
(2010)
Doi:10.1246/bcsj.41.628
(1968)
Synthesis of 5,7-dihydroxy-6-methoxy-2-(2-hydroxy-4-methoxyphenyl)-4H-1-benzopyran- 4-one and reassignment of structure of tamaridone

Doi:10.1080/00397919708006071
(1997)
Regioselective oxidation of the hydroxyl group in polyhydroxylated triterpenes by the indirect anodic oxidation method

Doi:10.1248/cpb.45.570
(1997)
One-pot synthesis of 1,2/3-triols from the allylic hydroperoxides catalyzed by zeolite-confined osmium(0) nanoclusters

Doi:10.1016/j.molcata.2013.06.013
(2013)
Electrocatalysis at Redox Polymer Electrodes with Separation of the Catalytic and Charge Propagation Roles. Reduction of O2 to H2O2 as Catalyzed by Cobalt(II) Tetrakis(4-N-methylpyridyl)porphyrin

Doi:10.1021/ja00298a008
(1985)

Article Doi