
Tetrahedron p. 2775 - 2784 (1997)
Update date:2022-08-03
Topics:
Baumgartner, Hansruedi
O'Sullivan, Anthony C.
In an effort to mimic the anthelmintic and insecticidal activities of kainic 1 and domoic 2 acids with compounds of simpler structure and much easier accessibility, the highly functionalised imidazoIines 4, 27, and 28 were prepared. This involved a synthesis of suitably protected β-aminoglutamic acid derivatives as key intermediates, which were condensed with orthoesters and deprotected to yield the desired compounds.
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