Enantioselective synthesis of haminol-1, an alarm pheromone of a Mediterranean mollusc

Article abstract of DOI:10.1016/S0957-4166(97)00025-6

The first enantioselective synthesis of (-)-(R)-haminol-1 is described in this paper. The chiral part of the molecule was prepared by reduction of an optically active β-ketosulfoxide. The all-trans trienic part was stereoselectively synthesized via reductive elimination of a 1,6-dibenzoate-2,4-diene with sodium amalgam.