Bioorganic and Medicinal Chemistry Letters p. 437 - 442 (1997)
Update date:2022-08-02
Topics:
Horino, Haruhiko
Mimura, Tetsuya
Ohta, Masahiro
Kubo, Hideo
Kitagawa, Masayuki
Synthesis and hypotensive activity of trans-3,4-dihydro-3-hydroxy-4-[(5-oxo-3,4-diazabicyclo[4.1.0]hept-2-en-2 -yl)oxy]-2H-1-benzopyrans and their congeners are described. Compounds (-)-9eB and (-)-20B were highly potent ATP-sensitive potassium channel openers.
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(1990)
