Studies on aromatase inhibitors. III. Synthesis and biological evaluation of [(4-bromobenzyl)(4-cyanophenyl)amino]azoles and their azine analogs

DOI: 10.1248/cpb.45.482

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 482 - 486 (1997)

Update date:2022-08-02

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Authors:

Okada, Minoru

Yoden, Toru

Kawaminami, Eiji

Shimada, Yoshiaki

Kudoh, Masafumi

Isomura, Yasuo

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Article abstract of DOI:10.1248/cpb.45.482

A series of [(4-bromobenzyl)(4-cyanophenyl)amino]azoles and their azine analogs, which have the side chain of the selective aromatase inhibitor YM511, were synthesized and evaluated for aromatase-inhibitory activity (in vitro) and for pregnant mare serum

Full text of DOI:10.1248/cpb.45.482

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