Bioorganic and Medicinal Chemistry Letters p. 663 - 668 (1997)
Update date:2022-07-30
Topics:
Tata, James R.
Nargund, Ravi P.
Murphy, Marcia M.
Johnston, David B. R.
Patchett, Arthur A.
Cheng, Kang
Wei, Liente
Chan, Wanda W.-S.
Butler, Bridget
Jacks, Thomas M.
Hickey, Gerard
Smith, Roy
The synthesis and activities of a series of spiroindane growth hormone secretagogues is reported. Modification of the benzylic position of the spiroindane has resulted in a dramatic increase in potency resulting in subnanomolar peptidomimetic growth hormone secretagogues. In vivo data demonstrating the good oral activity of these analogs is reported.
View MoreChangzhou naidechemical Co.Ltd
Contact:+86-519-82589807
Address:NO.25,Houyang street,Jintan,Changzhou City
Contact:+86-025-52406782
Address:8 Taizishan Rd., Yanjiang Industrial Development Area, Nanjing, Jiangsu, China.
Anhui Dexinjia Biopharm Co., Ltd
Contact:+86-531-82375818
Address:9 Hexie Road, kaifaqu, Taihe
Suzhou Howsine Biological Technology Co.,Ltd(expird)
website:http://www.howsine.com
Contact:86-512-67262751
Address:No 3,Weihua Road ,Suzhou Industrial Park ,Jiangsu ,China.
Shanghai Mio Chemical Co., Ltd
Contact:0086 21- 64401188-622
Address:16 Floor NO.2 Jiefang Building, No. 4855 Dushi Road, 201100 Shanghai, P.R.China
Doi:10.1021/ja01856a032
(1941)Doi:10.1021/jo962371x
(1997)Doi:10.1515/znb-1999-0517
(1999)Doi:10.1016/S0040-4039(97)00966-0
(1997)Doi:10.1016/S0008-6215(97)00032-3
(1997)Doi:10.1021/jo01018a035
(1965)
