Electrochemical removal of the picolinoyl group under mild acidic conditions, application to the protection of amines in peptide synthesis

DOI: 10.1016/S0040-4039(97)00362-6

Source and publish data:

Tetrahedron Letters p. 2283 - 2286 (1997)

Update date:2022-08-05

Topics: Isolation and Purification Peptide Synthesis Monitoring Conditions Electrolysis Electrochemical Deprotection Apparatus

Authors:

Auzeil, Nicolas

Dutruc-Rosset, Gilles

Largeron, Martine

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(97)00362-6

The picolinoyl group can be used as a convenient protective group for amines in peptide chemistry. Deprotection is performed by electrochemical reduction under mild acidic conditions.

Full text of DOI:10.1016/S0040-4039(97)00362-6

Products guided by the article

Product name:L-Phenylalanine, N-(2-pyridinylcarbonyl)-L-tryptophylglycyl-, phenylmethyl ester

Cas No:189580-68-5

R&D Labs maybe for 189580-68-5

Anhui Gusheng Import&Export CO.,LTD

Contact:86-551-63662296

Address:Jinzhai Road NO.162 ,hefei, china
YingYing Pharmaceutical Co.,Ltd

Contact:86-18854126208

Address:55#, yingxiongshan road
Jiaozuo Zhongwen Trading Coporation Limited

Contact:--

Address:East Renmin Road
Lishui Nanming Chemical Co., Ltd(expird)

Contact:+86-0578-2134101，2697830

Address:No.19 Tongji Road Shuige Industrial zone
Suzhou Health Chemicals Co., Ltd.

website:http://www.healthchems.com

Contact:13776257979

Address:No. 338, Jingang Avenue,

Relevant to this article

Synthesis of functionalized epoxides by copper-catalyzed alkylative epoxidation of allylic alcohols with alkyl nitriles

Doi:10.1021/acs.orglett.5b00571
(2015)
C-6 allylated pyranosides for the synthesis of complex oxygenated tetrahydrofurans

Doi:10.1016/S0040-4020(97)00282-2
(1997)
Synthesis of macrocyclic, potential inhibitors using a generic scaffold

Doi:10.1021/jo025615o
(2002)
Inter- and Intramolecular Thermal Activation of sp³ C-H Bonds with Ruthenium Bisallyl Complexes

Doi:10.1021/om990229r
(1999)
A facile regioselective 1,6-O-diacetylation method of methyl- glycopyranosides and their dimethyl phosphonates

Doi:10.1080/00397919708006792
(1997)
Asymmetric synthesis of (S)-1-methyl-2-cyclohexen-1-ol, a constituent of the aggregation pheromone of Dendroctonus pseudotsugae

Doi:10.1016/S0040-4020(00)00402-6
(2000)

Article Doi