Synthesis and evaluation of 1,5,6-trideoxy-6,6-difluoro-1,5-imino-D-glucitol (1,6-dideoxy-6,6-difluoronojirimycin) as a glucosidase inhibitor

DOI: 10.1016/S0008-6215(97)00341-8

Source and publish data:

Carbohydrate Research p. 165 - 170 (1997)

Update date:2022-08-03

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Authors:

Szarek, Mark A.

Wu, Xinfu

Szarek, Walter A.

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Article abstract of DOI:10.1016/S0008-6215(97)00341-8

1,5,6-Trideoxy-6,6-difluoro-1,5-imino-D-glucitol hydrochloride (2) and 1,5,6-trideoxy-6,6-difluoro-1,5-imino-D-glucitol (3) have been synthesized from L-sorbose. The formation of the C-5 difluoromethyl group was accomplished by difluorination of a carbony

Full text of DOI:10.1016/S0008-6215(97)00341-8

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