Synthesis of 3-Amino-2-(3-indolyl)propanol and propanoate derivatives and preliminary cardiovascular evaluation in rats

Article abstract of DOI:10.1111/j.2042-7158.1997.tb06789.x

A series of tryptamine analogues has been prepared and tested for their 5-HT₁ receptor agonist properties. The incorporation of an alkoxy group at the C-5 position of the indole nucleus resulted in a short-lived and dose-dependent immediate ant